CNOT2 (phospho Ser101) Antibody

ProSci
Product Code: PSI-79-919
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-919-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.

Images

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Immunohistochemical analysis of paraffin-embedded human brain tissue using CNOT2 (Phospho-Ser101) antibody (left) or the same antibody preincubated with blocking peptide (right).
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Immunohistochemical analysis of paraffin-embedded human brain tissue using CNOT2 (Phospho-Ser101) antibody (left) or the same antibody preincubated with blocking peptide (right).

Further Information

Additional Names:
NOT2H, CDC36, CNOT2, HSPC131
Background:
The CCR4-NOT complex functions as general transcription regulation complex. Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. 5 isoforms of the human protein are produced by alternative splicing.
Background References:
  • Albert T.K., Nucleic Acids Res. 28:809-817(2000).
  • Zhang Q.-H., Genome Res. 10:1546-1560(2000).
  • Ota T., Nat. Genet. 36:40-45(2004).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CNOT2 (phospho Ser101) antibody was raised against a peptide sequence around phosphorylation site of Serine101 (S-L-S (p)-Q-G) derived from Human CNOT2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
4848
NCBI Official Name:
CCR4-NOT transcription complex, subunit 2
NCBI Official Symbol:
CNOT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
NP_001186231.1
Protein GI Number:
11640600
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of CNOT2 only when phosphorylated at serine 101.
Swissprot #:
Q9NZN8