Tip60 (phospho Ser90) Antibody
| Code | Size | Price |
|---|
| PSI-79-924-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
HTATIP, TI60, Tat-interactive protein-60
Background:
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Background References:
- Kamine J., Virology 216:357-366(1996).
- Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).
- Legube G., Gene 310:161-168(2003).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p)-P-E) derived from Human Tip60.
Modifications:
Phospho-Specific
NCBI Gene ID #:
10524
NCBI Official Name:
K(lysine) acetyltransferase 5
NCBI Official Symbol:
KAT5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
NP_006379.2
Protein GI Number:
36287069
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.
Swissprot #:
Q92993