JAK2 (phospho Tyr570) Antibody

ProSci
Product Code: PSI-79-790
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-790-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from JK cells (Lane 2), using JAK2 (Phospho-Tyr570) Antibody. The lane on the left is treated with antigen-specific peptide.

Western blot analysis of extracts from JK cells (Lane 2), using JAK2 (Phospho-Tyr570) Antibody. The lane on the left is treated with antigen-specific peptide.

Further Information

Additional Names:
JAK2, Janus kinase 2, kinase Jak2
Application Note:
Western Blot: 1:500~1:1000
Background:
Plays a role in leptin signaling and control of body weight.
Background References:
  • Saltzman A., Biochem. Biophys. Res. Commun. 246:627-633(1998).
  • Dalal I., Blood 91:844-851(1998).
  • Peeters P., Blood 90:2535-2540(1997).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
JAK2 (phospho Tyr570) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 570 (G-D-Y (p)-G-Q) derived from Human JAK2 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3717
NCBI Official Name:
Janus kinase 2
NCBI Official Symbol:
JAK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
125 kDa
Protein Accession #:
NP_004963.1
Protein GI Number:
4826776
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.
Swissprot #:
O60674