PKA-R2beta (phospho Ser113) Antibody

ProSci
Product Code: PSI-79-813
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-813-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2beta (Phospho-Ser113) Antibody. The lane on the right is treated with the antigen-specific peptide.

Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2beta (Phospho-Ser113) Antibody. The lane on the right is treated with the antigen-specific peptide.

Further Information

Additional Names:
KAP3, PRKAR2B, PKA R2-beta
Application Note:
Western Blot: 1:500~1:1000
Background:
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Background References:
  • Levy F.O., Mol. Endocrinol. 2:1364-1373(1988).
  • DeGiorgis J.A., J. Proteome Res. 4:306-315(2005).
  • Han G., Proteomics 8:1346-1361(2008)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PKA-R2beta (phospho Ser113) antibody was raised against a peptide sequence around phosphorylation site of Serine113 (R-R-A (p)-S-V) derived from Human PKA-R2beta.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5577
NCBI Official Name:
protein kinase, cAMP-dependent, regulatory, type II, beta
NCBI Official Symbol:
PRKAR2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
NP_002727.2
Protein GI Number:
47132585
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of PKA-R2beta only when phosphorylated at serine 113.
Swissprot #:
P31323