eNOS (phospho Thr494) Antibody
| Code | Size | Price |
|---|
| PSI-79-829-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
cNOS, EC-NOS, ECNOS, NOS, NOS3
Application Note:
Western Blot: 1:500~1:1000
Background:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Background References:
- Janssens S.P., J. Biol. Chem. 267:14519-14522(1992).
- Janssens S.P., J. Biol. Chem. 267:22694-22694(1992).
- Marsden P.A., FEBS Lett. 307:287-293(1992)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
eNOS (phospho Thr494) antibody was raised against a peptide sequence around phosphorylation site of threonine 494 (R-K-K (p)-T-F derived from Human eNOS .
Modifications:
Phospho-Specific
NCBI Gene ID #:
4846
NCBI Official Name:
nitric oxide synthase 3 (endothelial cell)
NCBI Official Symbol:
NOS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
140 kDa
Protein Accession #:
NP_000594.2
Protein GI Number:
40254422
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of eNOS only when phosphorylated at threonine 494.
Swissprot #:
P29474