Connexin 43 (phospho Ser265) Antibody

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ProSci
Product Code: PSI-79-878
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-878-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from HuvEc cells using Connexin 43 (Phospho-Ser265) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from HuvEc cells using Connexin 43 (Phospho-Ser265) Antibody. The lane on the right is treated with the antigen-specific peptide.

Documents

Further Information

Additional Names:
CX43, CXA1, CXN-43, GJA1
Application Note:
Western Blot: 1:500~1:1000
Background:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
Background References:
  • Toshihiko Toyofuku, J. Biol. Chem., May 1998; 273: 12725.
  • Toshihiko Toyofuku, J. Biol. Chem., Jan 1998; 273: 1519.
  • Masayuki Shimada, Biol Reprod, Apr 2001; 64: 1255.
  • Merry L. Lindsey, Circulation, Jun 2006; 113: 2919 - 2928.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Connexin 43 (phospho Ser265) antibody was raised against a peptide sequence around phosphorylation site of Serine 265 (Q-K-Y (p)-A-Y) derived from Human Connexin 43.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2697
NCBI Official Name:
gap junction protein, alpha 1, 43kDa
NCBI Official Symbol:
GJA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
NP_000156.1
Protein GI Number:
4504001
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
Connexin 43 antibody detects endogenous levels of Connexin 43 only when phosphorylated at Serine 265
Swissprot #:
P17302