B-Raf (phospho Thr753) Antibody
| Code | Size | Price |
|---|
| PSI-79-896-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
B-RAF, RAFB1, RMIL, p94
Application Note:
Western Blot: 1:500~1:1000
Background:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.
Background References:
- Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).
- Albert S., Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
- Scherer S.W., Science 300:767-772(2003)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
B-Raf (phospho Thr753) antibody was raised against a peptide sequence around phosphorylation site of threonine 753 (P-K-T (p)-P-L) derived from Human B-Raf.
Modifications:
Phospho-Specific
NCBI Gene ID #:
673
NCBI Official Name:
v-raf murine sarcoma viral oncogene homolog B1
NCBI Official Symbol:
BRAF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
NP_004324.2
Protein GI Number:
50403720
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of B-Raf only when phosphorylated at threonine 753
Swissprot #:
P15056