Claudin 7 (phospho Tyr210) Antibody

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ProSci
Product Code: PSI-79-904
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-904-0.1mg0.1mg£488.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from 3T3 cells (Lane 2), using Claudin 7 (Phospho-Tyr210) Antibody. The lane on the left is treated with antigen-specific peptide.
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Western blot analysis of extracts from 3T3 cells (Lane 2), using Claudin 7 (Phospho-Tyr210) Antibody. The lane on the left is treated with antigen-specific peptide.

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Further Information

Additional Names:
CEPTRL2, claudin 7, CLD7, CPETRL2, CLDN7
Application Note:
Western Blot: 1:500~1:1000
Background:
Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells.
Background References:
  • Keen T.J.; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
  • Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
  • The MGC Project Team; Genome Res. 14:2121-2127(2004).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Claudin 7 (phospho Tyr210) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 210 (S-K-E-Y (p)-V) derived from Human Claudin 7.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1366
NCBI Official Name:
claudin 7
NCBI Official Symbol:
CLDN7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_001171951.1
Protein GI Number:
311033475
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Claudin 7 only when phosphorylated at tyrosine 210.
Swissprot #:
O95471