GRIN2B (phospho Ser1303) Antibody
| Code | Size | Price |
|---|
| PSI-79-930-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
GRIN2B, NMDE2, NME2, NR2B, NR3
Application Note:
Western Blot: 1:500~1:1000
Background:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Background References:
- Adams S.L., Biochim. Biophys. Acta 1260:105-108(1995).
- Hess S.D., J. Pharmacol. Exp. Ther. 278:808-816(1996).
- Mandich P., Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GRIN2B (phospho Ser1303) antibody was raised against a peptide sequence around phosphorylation site of Serine 1303 (Q-H-S (p)-Y-D) derived from Human GRIN2B.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2904
NCBI Official Name:
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
NCBI Official Symbol:
GRIN2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
170 kDa
Protein Accession #:
NP_000825.2
Protein GI Number:
4504127
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of GRIN2B only when phosphorylated at serine 1303.
Swissprot #:
Q13224