ITGB1 (phospho Tyr795) Antibody
| Code | Size | Price |
|---|
| PSI-79-933-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CD29, FNRB, ITB1
Application Note:
Western Blot: 1:500~1:1000
Background:
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Background References:
- Argraves W.S., J. Cell Biol. 105:1183-1190(1987).
- Ota T., Nat. Genet. 36:40-45(2004).
- Bechtel S., BMC Genomics 8:399-399(2007).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ITGB1 (phospho Tyr795) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 795 (P-K-Y (p)-E-G) derived from Human ITGB1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3688
NCBI Official Name:
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
NCBI Official Symbol:
ITGB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
140 kDa
Protein Accession #:
NP_002202.2
Protein GI Number:
19743813
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of ITGB1 only when phosphorylated at tyrosine 795.
Swissprot #:
P05556