TUBA1/3/4 (phospho Tyr272) Antibody
| Code | Size | Price |
|---|
| PSI-79-938-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
TBA1, TBA1A, TBA4A, TUBA1
Application Note:
Western Blot: 1:500~1:1000
Background:
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.
Background References:
- Adler A.J., Bioorg. Med. Chem. 9:1967-1976(2001).
- Sugano S., Nat. Genet. 36:40-45(2004).
- Venter J.C., Submitted (JUL-2005).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TUBA1/3/4 (phospho Tyr272) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 272 (A-T-Y (p)-A-P) derived from Human TUBA1/3/4.
Modifications:
Phospho-Specific
NCBI Gene ID #:
7846/10376/84790/113457/7278/112714/7277
NCBI Official Name:
tubulin alpha 1a, tubulin alpha 1b, tubulin alpha 1c
NCBI Official Symbol:
TUBA1A, TUBA1B, TUBA1C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50-55 kDa
Protein Accession #:
NP_001257328.1
Protein GI Number:
17986283
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of TUBA1/3/4 only when phosphorylated at tyrosine 272.
Swissprot #:
Q71U36/P68363/Q9BQE3/Q13748/Q6PEY2/P68366