CSFR (phospho Tyr708) Antibody
| Code | Size | Price |
|---|
| PSI-79-941-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
C-FMS, CD115, CSF1R, FIM2, FMS
Application Note:
Western Blot: 1:500~1:1000
Background:
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.
Background References:
- Hampe A., Oncogene Res. 4:9-17(1989) .
- Andre C., Genomics 39:216-226(1997).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CSFR (phospho Tyr708) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 708 (K-K-Y (p)-V-R) derived from Human CSFR .
Modifications:
Phospho-Specific
NCBI Gene ID #:
1436
NCBI Official Name:
colony stimulating factor 1 receptor
NCBI Official Symbol:
CSF1R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
200 kDa
Protein Accession #:
NP_001275634.1
Protein GI Number:
27262659
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The Antibody detects endogenous levels of CSF1R only when phosphorylated at tyrosine 708.
Swissprot #:
P07333