EPHA7 (phospho Tyr791) Antibody
| Code | Size | Price |
|---|
| PSI-79-944-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
EHK3, EK11, HEK11
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.
Background References:
- Fox G.M., Oncogene 10:897-905(1995).
- Mungall A.J., Nature 425:805-811(2003).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
EPHA7 (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y (p)-T-T) derived from Human EPHA7 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
2045
NCBI Official Name:
EPH receptor A7
NCBI Official Symbol:
EPHA7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
NP_004431.1
Protein GI Number:
146345416
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791.
Swissprot #:
Q15375