Smad2 (phospho Ser465) Antibody
| Code | Size | Price |
|---|
| PSI-79-947-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
hMAD-2, JV18, JV18-1, MAD, hSMAD2
Application Note:
Western Blot: 1:500~1:1000
Background:
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
Background References:
- Riggins G.J., Nat. Genet. 13:347-349(1996).
- Zhang Y., Nature 383:168-172(1996).
- Eppert K., Cell 86:543-552(1996).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Smad2 (phospho Ser465) antibody was raised against a peptide sequence around phosphorylation site of Serine 465 (C-S-S (p)-M-S) derived from Human Smad2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
4087
NCBI Official Name:
SMAD family member 2
NCBI Official Symbol:
SMAD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
NP_001003652.1
Protein GI Number:
51173730
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Smad2 only when phosphorylated at serine 465.
Swissprot #:
Q15796