PKCD (phospho Tyr64) Antibody

Contact us
ProSci
Product Code: PSI-79-973
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-973-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

1 / 1
Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-PKCD (Tyr64) Antibody. The lane on the right is treated with the antigen-specific peptide.
❮❯

Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-PKCD (Tyr64) Antibody. The lane on the right is treated with the antigen-specific peptide.

Documents

Further Information

Additional Names:
KPCD, PKC-delta, PRKCD, kinase PKC-delta, nPKC-delta
Application Note:
Western Blot: 1:500~1:1000
Background:
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.
Background References:
  • Wie SM, et al. (2014)J Biol Chem. Adwan TS, et al. (2011)J Biol Chem 286, 35716-24. Lomonaco SL, et al. (2008) J Biol Chem 283, 17731-9.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PKCD (phospho Tyr64) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 64 (H-I-Y (p)-E-G) derived from Human PKCD.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5580
NCBI Official Name:
protein kinase C, delta
NCBI Official Symbol:
PRKCD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
NP_006245.2
Protein GI Number:
31377782
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of PKCD only when phosphorylated at tyrosine 64.
Swissprot #:
Q05655