Kv2.1 (phospho Ser805) Antibody

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ProSci
Product Code: PSI-79-975
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-975-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from K562 cells treated with TNF using Phospho-Kv2.1 (Ser805) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from K562 cells treated with TNF using Phospho-Kv2.1 (Ser805) Antibody. The lane on the right is treated with the antigen-specific peptide.

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Further Information

Additional Names:
DRK1, KCB1, KCNB1, Potassium channel Kv2.1, Potassium voltage-gated channel subfamily B member 1
Application Note:
Western Blot: 1:500~1:1000
Background:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
Background References:
  • McCord MC, Aizenman E (2013)Proc Natl Acad Sci U S A 110, 13988-93 . Norris CA, et al. (2012) J Neurosci 32, 8865-70 . Cerda O, Trimmer JS (2011)J Biol Chem 286, 28738-48 .
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Kv2.1 (phospho Ser805) antibody was raised against a peptide sequence around phosphorylation site of serine805 (P-T-S (p)-P-K) derived from Human Kv2.1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
2745
NCBI Official Name:
glutaredoxin (thioltransferase)
NCBI Official Symbol:
GLRX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
96 kDa
Protein Accession #:
NP_004966.1
Protein GI Number:
4826784
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of Kv2.1 only when phosphorylated at serine 805.
Swissprot #:
Q14721