MKP-1/2 (phospho Ser296/318) Antibody

ProSci
Product Code: PSI-79-997
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-997-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from K562 cells treated with Heatshock using Phospho-MKP-1/2 (Ser296/318) Antibody. The lane on the right is treated with the antigen-specific peptide.

Western blot analysis of extracts from K562 cells treated with Heatshock using Phospho-MKP-1/2 (Ser296/318) Antibody. The lane on the right is treated with the antigen-specific peptide.

Further Information

Additional Names:
3CH134, CL100, Dual specificity protein phosphatase 1, DUS1, DUSP1
Application Note:
Western Blot: 1:500~1:1000
Background:
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Background References:
  • Lin YW, Yang JL (2006) J Biol Chem 281, 915-26
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MKP-1/2 (phospho Ser296/318) antibody was raised against a peptide sequence around phosphorylation site of serine 296/318 (I-I-S (p)-P-N) derived from Human MKP-1/2 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
1843/1846
NCBI Official Name:
dual specificity phosphatase 1, dual specificity phosphatase 4
NCBI Official Symbol:
DUSP1, DUSP4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_004408.1/ NP_001385.1
Protein GI Number:
4506095
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of MKP-1/2 only when phosphorylated at serine 296/318.
Swissprot #:
P28562/Q13115