CDC25A (phospho Ser178) Antibody
| Code | Size | Price |
|---|
| PSI-79-998-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CDC25M3, MPIP1, Dual specificity phosphatase Cdc25A, M-phase inducer phosphatase 1,
Application Note:
Western Blot: 1:500~1:1000
Background:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Background References:
- Chen MS, Ryan CE, Piwnica-Worms H (2003)Mol Cell Biol 23, 7488-97
- Hassepass I, Voit R, Hoffmann I (2003) J Biol Chem 278, 29824-9
- S?rensen CS, et al. (2003) Cancer Cell 3, 247-58
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CDC25A (phospho Ser178) antibody was raised against a peptide sequence around phosphorylation site of serine 178 (Q-N-S (p)-A-P) derived from Human CDC25A .
Modifications:
Phospho-Specific
NCBI Gene ID #:
993
NCBI Official Name:
cell division cycle 25A
NCBI Official Symbol:
CDC25A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
NP_001780.2
Protein GI Number:
42490758
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of CDC25A only when phosphorylated at serine 178.
Swissprot #:
P30304