NMDAR2B (phospho Tyr1336) Antibody

ProSci
Product Code: PSI-80-009
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-009-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from Jurkat cells treated with TNF using Phospho-NMDAR2B (Tyr1336) Antibody. The lane on the right is treated with the antigen-specific peptide.

Western blot analysis of extracts from Jurkat cells treated with TNF using Phospho-NMDAR2B (Tyr1336) Antibody. The lane on the right is treated with the antigen-specific peptide.

Further Information

Additional Names:
GRIN2B, hNR3, NME2, NR3, NMDE2
Application Note:
Western Blot: 1:500~1:1000
Background:
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Background References:
  • Morel V, et al. (2013) Eur J Pharmacol 721, 382-90. Peng HY, et al. (2010)Am J Physiol Renal Physiol 298, F109-17. Wu HY, et al. (2007) J Biol Chem 282, 20075-87.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NMDAR2B (phospho Tyr1336) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine1336 (S-P-Y (p)-A-H) derived from Human NMDAR2B.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2904
NCBI Official Name:
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
NCBI Official Symbol:
GRIN2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
150 kDa
Protein Accession #:
NP_000825.2
Protein GI Number:
4504127
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of NMDAR2B only when phosphorylated at tyrosine 1336.
Swissprot #:
Q13224