Vinculin (phospho Tyr821) Antibody
| Code | Size | Price |
|---|
| PSI-80-022-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
Vinculin
Application Note:
Western Blot: 1:500~1:1000
Background:
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Background References:
- Subauste MC, et al. (2004) J Cell Biol 165, 371-81
- Olsen JV, et al. (2010) Sci Signal 3, ra3
- J?rgensen C, et al. (2009) Science 326, 1502-9
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Vinculin (phospho Tyr821) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 821 (S-G-Y (p)-R-I) derived from Human Vinculin.
Modifications:
Phospho-Specific
NCBI Gene ID #:
7414
NCBI Official Name:
vinculin
NCBI Official Symbol:
VCL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
123 kDa
Protein Accession #:
NP_003364.1
Protein GI Number:
4507877
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of Vinculin only when phosphorylated at tyrosine 821.
Swissprot #:
P18206