STAT5A/B (phospho Ser725/730) Antibody

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ProSci
Product Code: PSI-80-026
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-026-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from Jurkat cells treated with EGF using Phospho-STAT5A/B (Ser725/730) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from Jurkat cells treated with EGF using Phospho-STAT5A/B (Ser725/730) Antibody. The lane on the right is treated with the antigen-specific peptide.

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Further Information

Additional Names:
Signal transducer and activator of transcription 5B, STA5B, STAT5, transcription factor STAT5B,
Application Note:
Western Blot: 1:500~1:1000
Background:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Background References:
  • Ross JA, et al. (2010) J Biol Chem 285, 3582-91
  • Uddin S, et al. (2003) Biochem Biophys Res Commun 308, 325-30
  • Xue HH, et al. (2002) Int Immunol 14, 1263-71
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
STAT5A/B (phospho Ser725/730) antibody was raised against a peptide sequence around phosphorylation site of serine725/730 (A-P-S (p)-P-A) derived from Human STAT5A/B .
Modifications:
Phospho-Specific
NCBI Gene ID #:
6776/6777
NCBI Official Name:
signal transducer and activator of transcription 5A, signal transducer and activator of transcription 5B
NCBI Official Symbol:
STAT5A, STAT5B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
NP_001275647.1/ NP_036580.2
Protein GI Number:
4504281
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of STAT5A/B only when phosphorylated at serine 725/ serine 730.
Swissprot #:
P42229/P51692