Calmodulin (phospho Thr79/Ser81) Antibody

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ProSci
Product Code: PSI-80-027
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-027-0.1mg0.1mg£488.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from HeLa tissue using Calmodulin (Phospho-Thr79/Ser81) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from HeLa tissue using Calmodulin (Phospho-Thr79/Ser81) Antibody. The lane on the right is treated with the antigen-specific peptide.

Documents

Further Information

Additional Names:
CALM, CALM1, CALM2, CALM3, CAM
Application Note:
Western Blot: 1:500~1:1000
Background:
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Background References:
  • Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76
  • Arrigoni G, et al. (2004) Biochemistry 43, 12788-98
  • Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Calmodulin (phospho Thr79/Ser81) antibody was raised against a peptide sequence around phosphorylation site of threonine79/serine81 (K-D-T (p)-D-S (p)-E-E) derived from Human Calmodulin .
Modifications:
Phospho-Specific
NCBI Gene ID #:
808
NCBI Official Name:
calmodulin 3 (phosphorylase kinase, delta)
NCBI Official Symbol:
CALM3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
NP_005175.2
Protein GI Number:
58218968
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of Calmodulin only when phosphorylated at threonine 79/serine 81.
Swissprot #:
P62158