VEGFR1 (phospho Tyr1213) Antibody

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ProSci
Product Code: PSI-80-034
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-034-0.1mg0.1mg£488.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from HeLa cells treated with UV using Phospho-VEGFR1 (Tyr1213) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from HeLa cells treated with UV using Phospho-VEGFR1 (Tyr1213) Antibody. The lane on the right is treated with the antigen-specific peptide.

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Further Information

Additional Names:
FLT, FLT1, FRT, Flt-1, Fms-like tyrosine kinase 1
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Background References:
  • Raghu H, et al. (2012) Mol Oncol 6, 33-47
  • Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54
  • Ito N, Wernstedt C, Engstr?m U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
VEGFR1 (phospho Tyr1213) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 1213 (V-R-Y (p)-V-N) derived from Human VEGFR1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2321
NCBI Official Name:
fms-related tyrosine kinase 1
NCBI Official Symbol:
FLT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
NP_001153392.1
Protein GI Number:
143811474
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of VEGFR1 only when phosphorylated at tyrosine 1213.
Swissprot #:
P17948