Estrogen Receptor- beta (phospho Ser105) Antibody

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ProSci
Product Code: PSI-80-046
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-046-0.1mg0.1mg£488.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from HepG2 tissue using Estrogen Receptor- beta (Phospho-Ser105) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from HepG2 tissue using Estrogen Receptor- beta (Phospho-Ser105) Antibody. The lane on the right is treated with the antigen-specific peptide.

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Further Information

Additional Names:
ESR2, ESTRB, Estrogen receptor beta, NR3A2,
Application Note:
Western Blot: 1:500~1:1000
Background:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Background References:
  • Hamilton-Burke W, et al. (2010)Am J Pathol 177, 1079-86. St-Laurent V, Sanchez M, Charbonneau C, Tremblay A (2005) J Steroid Biochem Mol Biol 94, 23-37. Tremblay A, Tremblay GB, Labrie F, Gigu?re V (1999) Mol Cell 3, 513-9 .
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Estrogen Receptor- beta (phospho Ser105) antibody was raised against a peptide sequence around phosphorylation site of serine105 (Q-R-S (p)-P-W) derived from Human Estrogen Receptor- beta.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2100
NCBI Official Name:
estrogen receptor 2 (ER beta)
NCBI Official Symbol:
ESR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
NP_001035365.1
Protein GI Number:
10835013
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of Estrogen Receptor- beta only when phosphorylated at serine 105.
Swissprot #:
Q92731