PEA-15 (phospho Ser104) Antibody
| Code | Size | Price |
|---|
| PSI-79-799-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
PE15, PEA15, PED
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
Background References:
- Estelles A., J. Biol. Chem. 271:14800-14806(1996).
- Condorelli G., EMBO J. 17:3858-3866(1998).
- Wolford J.K., Gene 241:143-148(2000).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PEA-15 (phospho Ser104) antibody was raised against a peptide sequence around phosphorylation site of Serine 104 (I-P-S (p)-A-K) derived from Human PEA-15.
Modifications:
Phospho-Specific
NCBI Gene ID #:
8682
NCBI Official Name:
phosphoprotein enriched in astrocytes 15
NCBI Official Symbol:
PEA15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
NP_003759.1
Protein GI Number:
32470612
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of PEA-15 only when phosphorylated at serine 104.
Swissprot #:
Q15121