STMN1 (phospho Ser62) Antibody

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ProSci
Product Code: PSI-79-836
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-836-0.1mg0.1mg£488.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from COS cells treated with nocodazole using STMN1 (Phospho-Ser62) Antibody. The lane on the right is treated with the antigen-specific peptide.
2 / 2
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STMN1 (Phospho-Ser62) antibody (left) or the same antibody preincubated with blocking peptide (right).
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Western blot analysis of extracts from COS cells treated with nocodazole using STMN1 (Phospho-Ser62) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STMN1 (Phospho-Ser62) antibody (left) or the same antibody preincubated with blocking peptide (right).

Documents

Further Information

Additional Names:
LAG, LAP18, pp19, PR22, STN1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.
Background References:
  • Zhu X.-X., J. Biol. Chem. 264:14556-14560(1989).
  • Maucuer A., FEBS Lett. 264:275-278(1990).
  • Melhem R.F., J. Biol. Chem. 266:17747-17753(1991).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
STMN1 (phospho Ser62) antibody was raised against a peptide sequence around phosphorylation site of Serine 62 (R-R-K (p)-S-H) derived from Human STMN1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3925
NCBI Official Name:
STMN1
NCBI Official Symbol:
STMN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
NP_005554.1
Protein GI Number:
51895905
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of STMN1 only when phosphorylated at serine 62.
Swissprot #:
P16949