CRMP-2 (phospho Thr509) Antibody
| Code | Size | Price |
|---|
| PSI-79-905-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CRMP2, N2A3, TOAD-64, DPYL2, ULIP2
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Background References:
- Miki Y., Science 266:66-71(1994).
- Smith T.M., Genome Res. 6:1029-1049(1996).
- Wilson C.A., Oncogene 14:1-16(1997).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CRMP-2 (phospho Thr509) antibody was raised against a peptide sequence around phosphorylation site of threonine 509 (S-V-T (p)-P-K) derived from Human CRMP-2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1808
NCBI Official Name:
dihydropyrimidinase-like 2
NCBI Official Symbol:
DPYSL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
NP_001377.1
Protein GI Number:
3122051
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.
Swissprot #:
Q16555