MAPKAPK2 (phospho Ser272) Antibody
| Code | Size | Price |
|---|
| PSI-79-915-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
MAPK2; , MAPKAPK2, RPS6KC1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Background References:
- Zu Y.-L., Biochem. Biophys. Res. Commun. 200-1118-1124(1994).
- The MGC Project Team; Genome Res. 14:2121-2127(2004).
- Stokoe D., Biochem. J. 296:843-849(1993).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MAPKAPK2 (phospho Ser272) antibody was raised against a peptide sequence around phosphorylation site of Serine 272 (A-I-S (p)-P-G) derived from Human MAPKAPK2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
9261
NCBI Official Name:
mitogen-activated protein kinase-activated protein kinase 2
NCBI Official Symbol:
MAPKAPK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_116584.2
Protein GI Number:
32481209
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of MAPKAPK2 only when phosphorylated at serine 272.
Swissprot #:
P49137