TAL-1 (phospho Ser122) Antibody
| Code | Size | Price |
|---|
| PSI-79-923-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
SCL, TAL1, TCL5
Application Note:
Western Blot: 1:500~1:1000
Background:
TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.
Background References:
- Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
- Gregory S.G., Nature 441:315-321(2006).
- Chen Q., J. Exp. Med. 172:1403-1408(1990).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p)-P-P) derived from Human TAL-1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
6886
NCBI Official Name:
T-cell acute lymphocytic leukemia 1
NCBI Official Symbol:
TAL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_001274276.1
Protein GI Number:
4507363
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.
Swissprot #:
P17542