CD289 Antibody [M9.D6] (FITC)
| Code | Size | Price |
|---|
| PSI-76-979-0.1mg | 0.1mg | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: M9.D6
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, Tlr9
Background:
The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system?s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Background References:
- Walzer, T., Blry, M., Chaix, J., Fuseri, N., Chasson, L., Robbins, S. H., ... Vivier, E. (2007). Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.Proceedings of the National Academy of Sciences,104(9), 3384-3389.
- Joncker, N. T., Fernandez, N. C., Treiner, E., Vivier, E., Raulet, D. H. (2009). NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model.The Journal of Immunology,182(8), 4572-4580.
- Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., ... Mandelboim, O. (2006). Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1.Nature immunology,7(5), 517-523.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
81897
NCBI Official Name:
toll-like receptor 9
NCBI Official Symbol:
Tlr9
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9).
Swissprot #:
Q9EQU3
User NOte:
Optimal dilutions for each application to be determined by the researcher.