CD83 Antibody [Michel17] (PE)
| Code | Size | Price |
|---|
| PSI-76-317-0.1mg | 0.1mg | £601.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG1
Antibody Clonality: Monoclonal
Antibody Clone: Michel17
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
Cd83, Cd83
Background:
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein. CD83 is expressed mainly on activated lymphocytes and mature dendritic cells and it plays a role in T cell development. The Michel-17 antibody does not induce an activation signal on dendritic or T cells.
Background References:
- Cramer, S. O., Trumpfheller, C., Mehlhoop, U., Mor, S., Fleischer, B., von Bonin, A. (2000). Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells.International immunology,12(9), 1347-1351.
- Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B., Von Bonin, A. (2003). Enhanced Activation of CD83Positive T Cells*.Scandinavian journal of immunology,58(3), 306-311.
- Breloer, M., Fleischer, B. (2008). CD83 regulates lymphocyte maturation, activation and homeostasis.Trends in immunology,29(4), 186-194.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12522
NCBI Official Name:
CD83 antigen
NCBI Official Symbol:
Cd83
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein.
Swissprot #:
O88324
User NOte:
Optimal dilutions for each application to be determined by the researcher.