CD144 Antibody [BV13] (PE)
| Code | Size | Price |
|---|
| PSI-76-864-0.025mg | 0.025mg | £373.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: BV13
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
7B4, Vec, VECD, Cd144, VEcad, VE-Cad, AA408225, Cdh5
Background:
The BV13 monoclonal antibody specifically reacts with mouse CD144 (VE-Cadherin), a 120 kDA type II Cadherin. CD144 is a hemophilic adhesion molecule of the endothelial cell line essential to maintaining cell layer integrity. It is involved in cell growth inhibition, migration, and survival.
Background References:
- Noelle, R. J., Roy, M., Shepherd, D. M., Stamenkovic, I., Ledbetter, J. A., Aruffo, A. (1992). A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.Proceedings of the National Academy of Sciences,89(14), 6550-6554.
- Roy, M., Aruffo, A., Ledbetter, J., Linsley, P., Kehry, M., Noelle, R. (1995). Studies on the interdependence of gp39 and B7 expression and function during antigenspecific immune responses.European journal of immunology,25(2), 596-603.
- Van den Eertwegh, A. J., Noelle, R. J., Roy, M. E. E. N. A. K. S. H. I., Shepherd, D. M., Aruffo, A., Ledbetter, J. A., ... Claassen, E. (1993). In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate TB cell interactions.The Journal of experimental medicine,178(5), 1555-1565.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12562
NCBI Official Name:
cadherin 5
NCBI Official Symbol:
Cdh5
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Cancer
SPECIFICITY:
The BV13 monoclonal antibody specifically reacts with mouse CD144 (VE-Cadherin), a 120 kDA type II Cadherin.
Swissprot #:
P55284
User NOte:
Optimal dilutions for each application to be determined by the researcher.