CD30 Antibody [mCD30.1]
| Code | Size | Price |
|---|
| PSI-76-018-0.5mg | 0.5mg | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: Armenian Hamster IgG
Antibody Clonality: Monoclonal
Antibody Clone: mCD30.1
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
Ki, Cd30, Ki-1, D1S166E, Tnfrsf8
Background:
The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.
Background References:
- Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2.Diabetes,49(9), 1612-1616.
- Falini, B., Pileri, S., Pizzolo, G., D, H., Flenghi, L., Stirpe, F., ... Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.BLOOD-NEW YORK-,85, 1-1.
- Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., Miller, J. F. (1999). CD 30 prevents Tcell responses to nonlymphoid tissues.Immunological reviews,169(1), 23-29.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
21941
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 8
NCBI Official Symbol:
Tnfrsf8
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Apoptosis,Functional Assays
SPECIFICITY:
The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily.
Swissprot #:
Q60846
User NOte:
Optimal dilutions for each application to be determined by the researcher.