CD38 Antibody [90]
| Code | Size | Price |
|---|
| PSI-76-755-0.5mg | 0.5mg | £633.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 90
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
ADPRC 1, Cd38-rs1, Cd38
Background:
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Background References:
- Gonzlez-lvaro, I., Domnguez-Jimnez, C., Ortiz, A. M., Nez-Gonzlez, V., Roda-Navarro, P., Fernndez-Ruiz, E., ... Snchez-Madrid, F. (2006). Interleukin-15 and interferon- gammaparticipate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production.Arthritis research therapy,8(4), R88.
- Katagiri, T., Qi, Z., Ohtake, S., Nakao, S. (2011). GPIanchored proteindeficient T cells in patients with aplastic anemia and lowrisk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure.European journal of haematology,86(3), 226-236.
- Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J., Thorley-Lawson, D. A. (1991). Expression of the Blast-1 activation/adhesion molecule and its identification as CD48.The Journal of immunology,146(7), 2192-2200.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12494
NCBI Official Name:
CD38 antigen
NCBI Official Symbol:
Cd38
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Functional Assays
SPECIFICITY:
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein.
Swissprot #:
P56528
User NOte:
Optimal dilutions for each application to be determined by the researcher.