CD31 Antibody [390]
| Code | Size | Price |
|---|
| PSI-76-167-0.5mg | 0.5mg | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 390
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
Cd31, Pecam, C85791, PECAM-1, Pecam1
Background:
The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1). CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Background References:
- HORENSTEIN, A., STOCKINGER, H., Imhof, B., MALAVASI, F. (1998). CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J,330, 1129-1135.
- Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., ... Albelda, S. M. (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development.Development,120(9), 2539-2553.
- DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., ... Albelda, S. M. (1997). Involvement of endothelial PECAM-1/CD31 in angiogenesis.The American journal of pathology,151(3), 671.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
18613
NCBI Official Name:
platelet/endothelial cell adhesion molecule 1
NCBI Official Symbol:
Pecam1
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Cancer,Functional Assays
SPECIFICITY:
The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1).
Swissprot #:
Q08481
User NOte:
Optimal dilutions for each application to be determined by the researcher.