CD1d Antibody [1B1]
| Code | Size | Price |
|---|
| PSI-76-086-0.5mg | 0.5mg | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 1B1
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
Cd1a, Cd1d, CD1.1, Ly-38, AI747460, Cd1d1
Background:
The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules. CD1d is expressed by mouse leukocytes, epithelial cells, thymocytes, and dendritic cells and is the only molecules in the CD1 family to have been found in the mouse. The 1B1 antibody detects CD1d in association with the Beta2m molecule.
Background References:
- Szalay, G., Ladel, C. H., Blum, C., Brossay, L., Kronenberg, M., Kaufmann, S. H. (1999). Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF--beta-2 and Th1 cytokines and ameliorates listeriosis in mice.The Journal of Immunology,162(12), 6955-6958.
- Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M., Bendelac, A. (1998). CD1. 1 expression by mouse antigen-presenting cells and marginal zone B cells.The Journal of Immunology,160(7), 3121-3127.
- Amano, M., Baumgarth, N., Dick, M. D., Brossay, L., Kronenberg, M., Herzenberg, L. A., Strober, S. (1998). CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: -beta-2-microglobulin-dependent and independent forms.The Journal of Immunology,161(4), 1710-1717.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12479
NCBI Official Name:
CD1d1 antigen
NCBI Official Symbol:
Cd1d1
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Innate Immunity
SPECIFICITY:
The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules.
Swissprot #:
P11609
User NOte:
Optimal dilutions for each application to be determined by the researcher.