CD24 Antibody [M1/69]
| Code | Size | Price |
|---|
| PSI-76-402-0.5mg | 0.5mg | £633.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: M1/69
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
HSA, Cd24, Ly-52, nectadrin, Cd24a
Background:
The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein. CD24 is known as the Heat Stable Antigen (HAS or HsAG) and is found on epithelial cells, thymocytes, monocytes, erythrocytes, granulocytes, dendritic cells and lymphocytes to the exclusion of NK cells. It is useful in delineating the stages of lymphocyte development and is involved in the costimulation of CD4+ T cells by B cells. CD62P (P-Selectin) is the reported ligand of CD24.
Background References:
- Alterman, L. A., Crispe, I. N., Kinnon, C. (1990). Characterization of the murine heatstable antigen: An hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies.European journal of immunology,20(7), 1597-1602.
- Crowley, M., Inaba, K., Witmer-Pack, M., Steinman, R. M. (1989). The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus.Cellular immunology,118(1), 108-125.
- Wenger, R. H., Rochelle, J. M., Seldin, M. F., Khler, G., Nielsen, P. J. (1993). The heat stable antigen (mouse CD24) gene is differentially regulated but has a housekeeping promoter.Journal of Biological Chemistry,268(31), 23345-23352.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12484
NCBI Official Name:
CD24a antigen
NCBI Official Symbol:
Cd24a
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Immunology,Functional Assays
SPECIFICITY:
The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein.
Swissprot #:
P24807
User NOte:
Optimal dilutions for each application to be determined by the researcher.