CD90 Antibody [G7]
| Code | Size | Price |
|---|
| PSI-76-082-0.5mg | 0.5mg | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG2c, kappa
Antibody Clonality: Monoclonal
Antibody Clone: G7
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
T25, CD90, Thy-1, Thy1.1, Thy1.2, Thy-1.2, Thy1
Background:
The G7 monoclonal antibody specifically reacts with mouse CD90, also known as thymus cell antigen-1 (Thy-1). CD90 is a 25-35 kDA GPI-anchored protein is the smallest member of the Ig superfamily. CD90 is expressed on thymocytes, neurons, hematopoietic stem cells, and T cells. It plays a role in T cell signal transduction and adhesion. The G7 antibody is reported to stimulate IL-2 secretion and T cell proliferation.
Background References:
- Kruisbeek, A. M., Shevach, E., Thornton, A. M. (2004). Proliferative assays for T cell function.Current protocols in immunology, 3-12.
- Nitta, H., Munger, W., Wilson, E., Ralston, R., Alila, H. (1997). Improved in situ immunodetection of leukocytes on paraffin-embedded mouse spleen.Cell Vision,4, 74-80.
- Gunter, K. C., Malek, T. R., Shevach, E. M. (1984). T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4.The Journal of experimental medicine,159(3), 716-730.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
21838
NCBI Official Name:
thymus cell antigen 1, theta
NCBI Official Symbol:
Thy1
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Immunology,Functional Assays
SPECIFICITY:
The G7 monoclonal antibody specifically reacts with mouse CD90, also known as thymus cell antigen-1 (Thy-1).
Swissprot #:
P01831
User NOte:
Optimal dilutions for each application to be determined by the researcher.