Fc epsilon Receptor I alpha Antibody [FceR1]

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ProSci
Product Code: PSI-77-175
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-77-175-0.5mg0.5mg£729.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Hamster
Antibody Isotype: Armenian Hamster IgG
Antibody Clonality: Monoclonal
Antibody Clone: FceR1
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Flow Cytometry
  • Functional Study
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
Storage:
The product should be stored undiluted at 4°C. Do not freeze.

Documents

Further Information

Additional Names:
FCE1A, FcER, FCER1A
Background:
The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
2205
NCBI Official Name:
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
NCBI Official Symbol:
FCER1A
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Innate Immunity
SPECIFICITY:
The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily.
Swissprot #:
P12319
User NOte:
Optimal dilutions for each application to be determined by the researcher.