CD81 Antibody [EAT-2 (Eat2)]

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ProSci
Product Code: PSI-76-183
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-76-183-0.1mg0.1mg£469.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Hamster
Antibody Isotype: Armenian Hamster IgG
Antibody Clonality: Monoclonal
Antibody Clone: EAT-2 (Eat2)
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Flow Cytometry
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
The product should be stored undiluted at 4°C. Do not freeze.

Documents

Further Information

Additional Names:
Tapa1, Tapa-1, Tspan28, Cd81
Background:
The Eat-2 monoclonal antibody reacts with mouse CD81, a 26kDA non-glycosylated transmembrane protein. CD81 is expressed broadly on B cells, T cells, NK cells, dendritic cells, fibroblasts, and endothelial cells. It plays a role in T cell development and is involved in B and T cell adhesion. The Eat-2 antibody is also reported to cross-react with the rat CD81 antigen.
Background References:
  • Miyazaki, T., M, U., Campbell, K. S. (1997). Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81.The EMBO journal,16(14), 4217-4225.
  • Boismenu, R., Rhein, M., Fischer, W. H., Havran, W. L. (1996). A role for CD81 in early T cell development.Science,271(5246), 198-200.
  • Maecker, H. T., Todd, S. C., Kim, E. C., Levy, S. (2000). Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies.Hybridoma,19(1), 15-22.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12520
NCBI Official Name:
CD81 antigen
NCBI Official Symbol:
Cd81
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
SPECIFICITY:
The Eat-2 monoclonal antibody reacts with mouse CD81, a 26kDA non-glycosylated transmembrane protein.
Swissprot #:
P35762
User NOte:
Optimal dilutions for each application to be determined by the researcher.