CD86 Antibody [24F] (FITC)
| Code | Size | Price |
|---|
| PSI-76-606-0.1mg | 0.1mg | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 24F
Regulatory Status: RUO
Target Species: Rat
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
B7-2, Cd86
Background:
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions.
The 24F antibody is capable of blocking the co-stimulatory activity of CD86.
Background References:
- Maeda, K., Sato, T., Azuma, M., Yagita, H., Okumura, K. (1997). Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology,9(7), 993-1000.
- Damoiseaux, J. G., Yagita, H., Okumura, K., van Breda Vriesman, P. J. (1998). Costimulatory molecules CD80 and CD86 in the rat
- tissue distribution and expression by antigen-presenting cells.Journal of leukocyte biology,64(6), 803-809.
- BLUESTONE, J. (1995). New perspectives of CD28-B7-mediated T cell costimulation.Immunity,2, 555-559.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
56822
NCBI Official Name:
CD86 molecule
NCBI Official Symbol:
Cd86
NCBI Organism:
Rattus norvegicus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.
User NOte:
Optimal dilutions for each application to be determined by the researcher.