ST2 Recombinant Protein

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ProSci
Product Code: PSI-96-428
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-96-428-0.2mg0.2mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

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Further Information

Additional Names:
IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
Background References:
  • Tago K., et al., 2001, Biochem. Biophys. Res. Commun. 285:1377-1383.
  • Schmitz J., et al., 2005, Immunity 23:479-490.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL33 at 10μg/ml (100μl/well) can bind rh IL1RL1 /ST2 Fc Chimera with a linear range of 0. 3-5μg/ml.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
9173
NCBI Official Name:
interleukin 1 receptor-like 1
NCBI Official Symbol:
IL1RL1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
61.0 kDa
Protein Accession #:
NP_003847
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q01638