DR6 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-730-0.2mg | 0.2mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
TNFRSF21, DR6, CD358, BM-018
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) is also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-κB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.
Background References:
- Pan G., et al., 1998, FEBS Lett. 431 (3): 351?356.
- Kuester M., et al., 2011, J. Mol. Biol. 409 (2): 189?201.
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
27242
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 21
NCBI Official Symbol:
TNFRSF21
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
60.2 kDa
Protein Accession #:
AAH17730
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O75509