TYRO3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-759-0.2mg | 0.2mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
TYRO3, BYK, DTK, RSE, SKY, TIF
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.
Background References:
- Shimojima M., et al., 2006, J. Virol. 80:10109-10116.
- Cosemans J.M., et al., 2010, J. Thromb. Haemost. 8:1797-1808.
- Heiring C., et al., 2004, J. Biol. Chem. 279:6952-6958.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
7301
NCBI Official Name:
TYRO3 protein tyrosine kinase
NCBI Official Symbol:
TYRO3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
68.2 kDa
Protein Accession #:
AAH51756
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q06418