BMPR1A Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-024-0.2mg | 0.2mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
BMPR-1A, ALK-3, 10q23del, ACVRLK3, CD292, SKR5
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2[1]. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.
Background References:
- Mishina Y, Starbuck MW , et al.,2004, J. Biol. Chem. 279 (26): 27560?6.
- Song L, F?ssler R, et al., 2007, Dev Biol. 301(1):276-86.
Buffer:
50 mM tris, 100 mM glycine, pH7.5.
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
657
NCBI Official Name:
bone morphogenetic protein receptor, type IA
NCBI Official Symbol:
BMPR1A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
42 kDa
Protein Accession #:
CAA80257
Purity:
>98% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P36894