CLEC4G Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-189-0.05mg | 0.05mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -71°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CLEC4G, LSECtin
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.
Background References:
- Liu W., et al., 2004, J Biol Chem. 279(18):18748-58.
- Powlesland AS., et al., 2008, J Biol Chem. 283(1):593-602.
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
339390
NCBI Official Name:
C-type lectin domain family 4, member G
NCBI Official Symbol:
CLEC4G
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
52.1 kDa
Protein Accession #:
Q6UXB4
Purity:
>85% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q6UXB4