Frizzled 7 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-335-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
FZD7, Frizzled-7, FzE3, Fz-7, hFz7
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.
Background References:
- Sagara N., et al., 1998, Biochem. Biophys. Res. Commun. 252:117-122.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
8324
NCBI Official Name:
frizzled class receptor 7
NCBI Official Symbol:
FZD7
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
43.3 kDa
Protein Accession #:
AAH15915
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O75084