CD122 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-463-0.05mg | 0.05mg | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL2RB, CD122, P70-75
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
Background References:
- Mulloy J.C., et al., 1996, J. Virol. 70:3599-3605.
- Lindholm C.K., 2002, Biochem. Biophys. Res. Commun. 296:929-936.
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
3560
NCBI Official Name:
interleukin 2 receptor, beta
NCBI Official Symbol:
IL2RB
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
50.7 kDa
Protein Accession #:
NP_000869.1
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P14784