SIGLEC5 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-691-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
SIGLEC5, OB-BP2, CD170, CD33L2
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Background References:
- Cornish A.L., et al., 1998, Blood 92:2123-2132.
- Patel N., et al., 1999, J. Biol. Chem. 274:22729-22738.
- Zhuravleva M.A., et al., 2008, J. Mol. Biol. 375:437-447.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
8778
NCBI Official Name:
sialic acid binding Ig-like lectin 5
NCBI Official Symbol:
SIGLEC5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
73 kDa
Protein Accession #:
AAH29896
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O15389