CD40 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-086-0.2mg | 0.2mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3).
Background References:
- Ferrari S., et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98:12614-12619,
- Singh J., et al., 1998, Protein Sci. 7:1124-1135.
Biological Activity:
Immobilized Human CD40, His Tag at 5ug/mL (100 uL/well) can bind Mouse CD40 Ligand, Fc Tag with a linear range of 2.6-16 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
C-His Tag
NCBI Gene ID #:
958
NCBI Official Name:
CD40 molecule, TNF receptor superfamily member 5
NCBI Official Symbol:
CD40
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
20 kDa
Protein Accession #:
P25942-1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P25942